Published on Saturday, April 7, 2012 by Kathy McCabe On April 10th of 1516, the first Jewish ghetto in the world was established in Venice Italy. The government officially confined the city’s Jews to this one small area of the city, in the Cannaregio district. The gates of the ghetto were closed upon nightfall and Jews were banned from leaving. During the day, they were required to identify themselves: the men had a c...